Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils

BACKGROUND: Mice are susceptible to infections with the rodent filarial nematode Litomosoides sigmodontis and develop immune responses that resemble those of human filarial infections. Thus, the L. sigmodontis model is used to study filarial immunomodulation, protective immune responses against fila...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Frohberger, Stefan J., Ajendra, Jesuthas, Surendar, Jayagopi, Stamminger, Wiebke, Ehrens, Alexandra, Buerfent, Benedikt C., Gentil, Katrin, Hoerauf, Achim, Hübner, Marc P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528299/
https://ncbi.nlm.nih.gov/pubmed/31109364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3502-z
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