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Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils

BACKGROUND: Mice are susceptible to infections with the rodent filarial nematode Litomosoides sigmodontis and develop immune responses that resemble those of human filarial infections. Thus, the L. sigmodontis model is used to study filarial immunomodulation, protective immune responses against fila...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Parasit Vectors
Päätekijät: Frohberger, Stefan J., Ajendra, Jesuthas, Surendar, Jayagopi, Stamminger, Wiebke, Ehrens, Alexandra, Buerfent, Benedikt C., Gentil, Katrin, Hoerauf, Achim, Hübner, Marc P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528299/
https://ncbi.nlm.nih.gov/pubmed/31109364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3502-z
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