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Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils

BACKGROUND: Mice are susceptible to infections with the rodent filarial nematode Litomosoides sigmodontis and develop immune responses that resemble those of human filarial infections. Thus, the L. sigmodontis model is used to study filarial immunomodulation, protective immune responses against fila...

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Publicat a:Parasit Vectors
Autors principals: Frohberger, Stefan J., Ajendra, Jesuthas, Surendar, Jayagopi, Stamminger, Wiebke, Ehrens, Alexandra, Buerfent, Benedikt C., Gentil, Katrin, Hoerauf, Achim, Hübner, Marc P.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528299/
https://ncbi.nlm.nih.gov/pubmed/31109364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3502-z
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