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Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer

BACKGROUND: The development of colorectal cancer (CRC) is a complicated multistep process that involves an accumulation of mutations in tumor suppressor genes and oncogenes. In the process of DNA replication, base mismatch often occurs due to various factors leading to abnormal expression of mismatc...

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Detalhes bibliográficos
Publicado no:World J Gastrointest Oncol
Main Authors: Wang, Shui-Ming, Jiang, Bin, Deng, Youping, Huang, Shu-Liang, Fang, Ming-Zhi, Wang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883179/
https://ncbi.nlm.nih.gov/pubmed/31798786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v11.i11.1065
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