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Amplicon deep sequencing improves Plasmodium falciparum genotyping in clinical trials of antimalarial drugs

Clinical trials monitoring malaria drug resistance require genotyping of recurrent Plasmodium falciparum parasites to distinguish between treatment failure and new infection occurring during the trial follow up period. Because trial participants usually harbour multi-clonal P. falciparum infections,...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Gruenberg, Maria, Lerch, Anita, Beck, Hans-Peter, Felger, Ingrid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883076/
https://ncbi.nlm.nih.gov/pubmed/31780741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54203-0
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