Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections

BACKGROUND: Amplicon deep sequencing permits sensitive detection of minority clones and improves discriminatory power for genotyping multi-clone Plasmodium falciparum infections. New amplicon sequencing and data analysis protocols are needed for genotyping in epidemiological studies and drug efficac...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Lerch, Anita, Koepfli, Cristian, Hofmann, Natalie E., Messerli, Camilla, Wilcox, Stephen, Kattenberg, Johanna H., Betuela, Inoni, O’Connor, Liam, Mueller, Ivo, Felger, Ingrid
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Methdology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682641/
https://ncbi.nlm.nih.gov/pubmed/29132317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4260-y
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