Wedelolactone-Loaded Micelles Ameliorate Doxorubicin-Induced Oxidative Injury in Podocytes by Improving Permeability and Bioavailability

Wedelolactone (WED) is commonly used for the treatment of doxorubicin (DOX)-induced kidney damage, but its efficacy is limited by its poor solubility and bioavailability. In this study, we developed a novel delivery system of WED-loaded micelles (WED-M) with Solutol(®) HS15 and lecithin at an optimi...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Feng, Liang, Li, Zhi-yong, Wang, Long, Li, Xing-hua, Chen, Ya-ping, Yang, Bing, Yang, Dang, Lian, Yuan-pei, Hou, Xue-feng, Li, Jun-hui, Ding, Shu-min, Jia, Xiao-bin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883003/
https://ncbi.nlm.nih.gov/pubmed/31824933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00333
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