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Bioavailability Enhancement of Paclitaxel via a Novel Oral Drug Delivery System: Paclitaxel-Loaded Glycyrrhizic Acid Micelles

Paclitaxel (PTX, taxol), a classical antitumor drug against a wide range of tumors, shows poor oral bioavailability. In order to improve the oral bioavailability of PTX, glycyrrhizic acid (GA) was used as the carrier in this study. This was the first report on the preparation, characterization and t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yang, Fu-Heng, Zhang, Qing, Liang, Qian-Ying, Wang, Sheng-Qi, Zhao, Bo-Xin, Wang, Ya-Tian, Cai, Yun, Li, Guo-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272134/
https://ncbi.nlm.nih.gov/pubmed/25756651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20034337
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