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Bioavailability Enhancement of Paclitaxel via a Novel Oral Drug Delivery System: Paclitaxel-Loaded Glycyrrhizic Acid Micelles

Paclitaxel (PTX, taxol), a classical antitumor drug against a wide range of tumors, shows poor oral bioavailability. In order to improve the oral bioavailability of PTX, glycyrrhizic acid (GA) was used as the carrier in this study. This was the first report on the preparation, characterization and t...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Yang, Fu-Heng, Zhang, Qing, Liang, Qian-Ying, Wang, Sheng-Qi, Zhao, Bo-Xin, Wang, Ya-Tian, Cai, Yun, Li, Guo-Feng
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272134/
https://ncbi.nlm.nih.gov/pubmed/25756651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20034337
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