Bioavailability Enhancement of Paclitaxel via a Novel Oral Drug Delivery System: Paclitaxel-Loaded Glycyrrhizic Acid Micelles

Paclitaxel (PTX, taxol), a classical antitumor drug against a wide range of tumors, shows poor oral bioavailability. In order to improve the oral bioavailability of PTX, glycyrrhizic acid (GA) was used as the carrier in this study. This was the first report on the preparation, characterization and t...

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Veröffentlicht in:Molecules
Hauptverfasser: Yang, Fu-Heng, Zhang, Qing, Liang, Qian-Ying, Wang, Sheng-Qi, Zhao, Bo-Xin, Wang, Ya-Tian, Cai, Yun, Li, Guo-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272134/
https://ncbi.nlm.nih.gov/pubmed/25756651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20034337
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