Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility

Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in TSC1 or TSC2, which encode proteins that negatively regulate mTOR complex 1 (mTORC1). TSC is associated with significant cognitive, psychiatric, and behavioral problems, collectively termed TSC-Associated Neurop...

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Vydáno v:Nat Commun
Hlavní autoři: Kosillo, Polina, Doig, Natalie M., Ahmed, Kamran M., Agopyan-Miu, Alexander H.C.W., Wong, Corinna D., Conyers, Lisa, Threlfell, Sarah, Magill, Peter J., Bateup, Helen S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882901/
https://ncbi.nlm.nih.gov/pubmed/31780742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13396-8
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