Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice

Synaptic inhibition plays a fundamental role in the information processing of neural circuits. It sculpts excitatory signals and prevents hyperexcitability of neurons. Owing to these essential functions, dysregulated synaptic inhibition causes a plethora of neurological disorders, including epilepsy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Kim, Hye Yun, Yang, Yong Ryoul, Hwang, Hongik, Lee, Ha-Eun, Jang, Hyun-Jun, Kim, Jeongyeon, Yang, Esther, Kim, Hyun, Rhim, Hyewhon, Suh, Pann-Ghill, Kim, Jae-Ick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882884/
https://ncbi.nlm.nih.gov/pubmed/31780806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54477-4
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