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Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice
Synaptic inhibition plays a fundamental role in the information processing of neural circuits. It sculpts excitatory signals and prevents hyperexcitability of neurons. Owing to these essential functions, dysregulated synaptic inhibition causes a plethora of neurological disorders, including epilepsy...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6882884/ https://ncbi.nlm.nih.gov/pubmed/31780806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54477-4 |
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