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Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

Cellular uptake is limiting for the efficacy of many cytotoxic drugs used to treat cancer. Identifying endocytic mechanisms that can be modulated with targeted, clinically-relevant interventions is important to enhance the efficacy of various cancer drugs. We identify that flotillin-dependent endocy...

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Publicado en:Sci Rep
Autores principales: Fekri, Farnaz, Abousawan, John, Bautista, Stephen, Orofiamma, Laura, Dayam, Roya M., Antonescu, Costin N., Karshafian, Raffi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882852/
https://ncbi.nlm.nih.gov/pubmed/31780775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54062-9
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