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Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

Cellular uptake is limiting for the efficacy of many cytotoxic drugs used to treat cancer. Identifying endocytic mechanisms that can be modulated with targeted, clinically-relevant interventions is important to enhance the efficacy of various cancer drugs. We identify that flotillin-dependent endocy...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Fekri, Farnaz, Abousawan, John, Bautista, Stephen, Orofiamma, Laura, Dayam, Roya M., Antonescu, Costin N., Karshafian, Raffi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882852/
https://ncbi.nlm.nih.gov/pubmed/31780775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54062-9
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