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TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction

TFEB is a basic helix-loop-helix transcription factor that confers protection against metabolic diseases such as atherosclerosis by targeting a network of genes involved in autophagy-lysosomal biogenesis and lipid catabolism. In this study, we sought to characterize the role of TFEB in adipocyte and...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Evans, Trent D., Zhang, Xiangyu, Jeong, Se-Jin, He, Anyuan, Song, Eric, Bhattacharya, Somashubhra, Holloway, Karyn B., Lodhi, Irfan J., Razani, Babak
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882500/
https://ncbi.nlm.nih.gov/pubmed/31690633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau2281
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