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Understanding the Mechanisms of Resistance to CAR T-Cell Therapy in Malignancies

Taking advantage of the immune system to exert an antitumor effect is currently a novel approach in cancer therapy. Adoptive transfer of T cells engineered to express chimeric antigen receptors (CARs) targeting a desired antigen has shown extraordinary antitumor activity, especially in refractory an...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Cheng, Jiali, Zhao, Lei, Zhang, Yuanyuan, Qin, Yun, Guan, Yuqi, Zhang, Tong, Liu, Chaohong, Zhou, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882288/
https://ncbi.nlm.nih.gov/pubmed/31824840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01237
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