Control of doxorubicin-induced, reactive oxygen-related apoptosis by glutathione peroxidase 1 in cardiac fibroblasts

Reactive oxygen formation plays a mechanistic role in the cardiotoxicity of doxorubicin, a chemotherapeutic agent that remains an important component of treatment programs for breast cancer and hematopoietic malignancies. To examine the role of doxorubicin-induced reactive oxygen species (ROS) in dr...

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Bibliographic Details
Published in:Biochem Biophys Rep
Main Authors: Doroshow, James H., Esworthy, R. Steven, Chu, Fong-Fong
Format: Artigo
Language:Inglês
Published: Elsevier 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881695/
https://ncbi.nlm.nih.gov/pubmed/31799454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100709
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