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NOX1 causes ileocolitis in mice deficient in glutathione peroxidase-1 and -2
We previously reported that mice deficient in two Se-dependent glutathione peroxidases, GPx1 and GPx2, have spontaneous ileocolitis. Disease severity depends on mouse genetic background. While C57BL/6J (B6) GPx1/2-DKO mice have moderate ileitis and mild colitis, 129S1Svlm/J (129) DKO mice have sever...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943970/ https://ncbi.nlm.nih.gov/pubmed/24374371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.12.018 |
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