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Direct visualization of human myosin II force generation using DNA origami-based thick filaments
The sarcomere, the minimal mechanical unit of muscle, is composed of myosins, which self-assemble into thick filaments that interact with actin-based thin filaments in a highly-structured lattice. This complex imposes a geometric restriction on myosin in force generation. However, how single myosins...
Gardado en:
| Publicado en: | Commun Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881340/ https://ncbi.nlm.nih.gov/pubmed/31799438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0683-0 |
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