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The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression
In the HIV-1 Thai RV144 vaccine trial—the only trial to demonstrate any vaccine efficacy to date—a three-variant haplotype within the Fc gamma receptor 2C gene (FCGR2C) modified the risk of HIV-1 acquisition. A similar vaccine regimen is currently being evaluated in South Africa in the HVTN702 trial...
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| Publié dans: | Genes Immun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881233/ https://ncbi.nlm.nih.gov/pubmed/30563969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-018-0053-9 |
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