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Biochemical Ligand Density Regulates YAP Translocation in Stem Cells through Cytoskeletal Tension and Integrins
Different tissue types are characterized by varying stiffness and biochemical ligands. Increasing substrate stiffness has been shown to trigger Yes-associated protein (YAP) translocation from cytoplasm to the nucleus, yet the role of ligand density in modulating mechanotransduction and stem cell fat...
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| Publicado no: | ACS Appl Mater Interfaces |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881158/ https://ncbi.nlm.nih.gov/pubmed/30789697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.8b21270 |
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