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Biochemical Ligand Density Regulates YAP Translocation in Stem Cells through Cytoskeletal Tension and Integrins

Different tissue types are characterized by varying stiffness and biochemical ligands. Increasing substrate stiffness has been shown to trigger Yes-associated protein (YAP) translocation from cytoplasm to the nucleus, yet the role of ligand density in modulating mechanotransduction and stem cell fat...

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Bibliografske podrobnosti
izdano v:ACS Appl Mater Interfaces
Main Authors: Stanton, Alice E., Tong, Xinming, Lee, Soah, Yang, Fan
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881158/
https://ncbi.nlm.nih.gov/pubmed/30789697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.8b21270
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