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Hydrogels with enhanced protein conjugation efficiency reveal stiffness-induced YAP localization in stem cells depends on biochemical cues

Polyacrylamide hydrogels have been widely used in stem cell mechanotransduction studies. Conventional conjugation methods of biochemical cues to polyacrylamide hydrogels suffer from low conjugation efficiency, which leads to poor attachment of human pluripotent stem cells (hPSCs) on soft substrates....

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Detalles Bibliográficos
Publicado en:Biomaterials
Main Authors: Lee, Soah, Stanton, Alice E., Tong, Xinming, Yang, Fan
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447317/
https://ncbi.nlm.nih.gov/pubmed/30826537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.02.021
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