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Hydrogels with enhanced protein conjugation efficiency reveal stiffness-induced YAP localization in stem cells depends on biochemical cues

Polyacrylamide hydrogels have been widely used in stem cell mechanotransduction studies. Conventional conjugation methods of biochemical cues to polyacrylamide hydrogels suffer from low conjugation efficiency, which leads to poor attachment of human pluripotent stem cells (hPSCs) on soft substrates....

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Bibliographische Detailangaben
Veröffentlicht in:Biomaterials
Hauptverfasser: Lee, Soah, Stanton, Alice E., Tong, Xinming, Yang, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447317/
https://ncbi.nlm.nih.gov/pubmed/30826537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.02.021
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