Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer

PURPOSE: Oral mucositis (OM) remains a common, debilitating toxicity of radiation therapy (RT) for head and neck cancer. The goal of this phase IIb, multi-institutional, randomized, double-blind trial was to compare the efficacy and safety of GC4419, a superoxide dismutase mimetic, with placebo to r...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Clin Oncol
Autori principali: Anderson, Carryn M., Lee, Christopher M., Saunders, Deborah P., Curtis, Amarinthia, Dunlap, Neal, Nangia, Chaitali, Lee, Arielle S., Gordon, Sharon M., Kovoor, Philip, Arevalo-Araujo, Roberto, Bar-Ad, Voichita, Peddada, Abhinand, Colvett, Kyle, Miller, Douglas, Jain, Anshu K., Wheeler, James, Blakaj, Dukagjin, Bonomi, Marcelo, Agarwala, Sanjiv S., Garg, Madhur, Worden, Francis, Holmlund, Jon, Brill, Jeffrey M., Downs, Matt, Sonis, Stephen T., Katz, Sanford, Buatti, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2019
Soggetti:
ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881100/
https://ncbi.nlm.nih.gov/pubmed/31618127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.01507
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi