Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer

PURPOSE: Oral mucositis (OM) remains a common, debilitating toxicity of radiation therapy (RT) for head and neck cancer. The goal of this phase IIb, multi-institutional, randomized, double-blind trial was to compare the efficacy and safety of GC4419, a superoxide dismutase mimetic, with placebo to r...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Clin Oncol
Hlavní autoři: Anderson, Carryn M., Lee, Christopher M., Saunders, Deborah P., Curtis, Amarinthia, Dunlap, Neal, Nangia, Chaitali, Lee, Arielle S., Gordon, Sharon M., Kovoor, Philip, Arevalo-Araujo, Roberto, Bar-Ad, Voichita, Peddada, Abhinand, Colvett, Kyle, Miller, Douglas, Jain, Anshu K., Wheeler, James, Blakaj, Dukagjin, Bonomi, Marcelo, Agarwala, Sanjiv S., Garg, Madhur, Worden, Francis, Holmlund, Jon, Brill, Jeffrey M., Downs, Matt, Sonis, Stephen T., Katz, Sanford, Buatti, John M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2019
Témata:
ORIGINAL REPORTS
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881100/
https://ncbi.nlm.nih.gov/pubmed/31618127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.01507
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky