First hyperpolarized [2-(13)C]pyruvate MR studies of human brain metabolism

We developed methods for the preparation of hyperpolarized (HP) sterile [2-(13)C]pyruvate to test its feasibility in first-ever human NMR studies following FDA-IND & IRB approval. Spectral results using this MR stable-isotope imaging approach demonstrated the feasibility of investigating human c...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Magn Reson
Auteurs principaux: Chung, Brian T., Chen, Hsin-Yu, Gordon, Jeremy, Mammoli, Daniele, Sriram, Renuka, Autry, Adam W., Le Page, Lydia M., Chaumeil, Myriam, Shin, Peter, Slater, James, Tan, Chou T., Suszczynski, Chris, Chang, Susan, Li, Yan, Bok, Robert A., Ronen, Sabrina M., Larson, Peder E.Z., Kurhanewicz, John, Vigneron, Daniel B.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880930/
https://ncbi.nlm.nih.gov/pubmed/31648132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2019.106617
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