TAZ functions as a tumor suppressor in multiple myeloma by downregulating MYC

Multiple myeloma (MM) is an incurable blood cancer that is often characterized by amplification and overexpression of the MYC oncogene. Despite efforts, direct targeting of MYC is not yet possible; therefore, alternative strategies to inhibit MYC activity are necessary. TAZ is a transcriptional coac...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Grieve, Stacy, Wajnberg, Gabriel, Lees, Miranda, Chacko, Simi, Weir, Jackson, Crapoulet, Nicolas, Reiman, Tony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2019
Gaiak:
Lymphoid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880893/
https://ncbi.nlm.nih.gov/pubmed/31743393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000374
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