Iodine-mediated hydration of alkynes on keto-functionalized scaffolds: mechanistic insight and the regiospecific hydration of internal alkynes

An iodine-mediated hydration reaction of alkynes serves as a green alternative to metal-catalyzed procedures. Previous work has shown that this method works well with terminal alkynes on keto-functionalized scaffolds, including 1,3-dicarbonyls and their heteroatom analogues. It was hypothesized that...

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Bibliografische gegevens
Gepubliceerd in:Beilstein J Org Chem
Hoofdauteurs: Lee, Zachary, Jones, Brandon R, Nkengbeza, Nyochembeng, Phillips, Michael, Valentine, Kayla, Stewart, Alexis, Sellers, Brandon, Shuber, Nicholas, Aiken, Karelle S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Beilstein-Institut 2019
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Letter
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880791/
https://ncbi.nlm.nih.gov/pubmed/31807207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.265
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