Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease

Human pluripotent stem cells (hPSCs) are a promising resource for the replacement of degenerated ventral midbrain dopaminergic (vmDA) neurons in Parkinson's disease. Despite recent advances in protocols for the in vitro generation of vmDA neurons, the asynchronous and heterogeneous nature of th...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: de Luzy, Isabelle R., Niclis, Jonathan C., Gantner, Carlos W., Kauhausen, Jessica A., Hunt, Cameron P.J., Ermine, Charlotte, Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880462/
https://ncbi.nlm.nih.gov/pubmed/31641054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1160-19.2019
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