Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease

Human pluripotent stem cells (hPSCs) are a promising resource for the replacement of degenerated ventral midbrain dopaminergic (vmDA) neurons in Parkinson's disease. Despite recent advances in protocols for the in vitro generation of vmDA neurons, the asynchronous and heterogeneous nature of th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: de Luzy, Isabelle R., Niclis, Jonathan C., Gantner, Carlos W., Kauhausen, Jessica A., Hunt, Cameron P.J., Ermine, Charlotte, Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880462/
https://ncbi.nlm.nih.gov/pubmed/31641054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1160-19.2019
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