Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno‐Free Conditions Restore Motor Deficits in Parkinsonian Rodents

Recent studies have shown evidence for the functional integration of human pluripotent stem cell (hPSC)‐derived ventral midbrain dopamine (vmDA) neurons in animal models of Parkinson’s disease. Although these cells present a sustainable alternative to fetal mesencephalic grafts, a number of hurdles...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Niclis, Jonathan C., Gantner, Carlos W., Alsanie, Walaa F., McDougall, Stuart J., Bye, Chris R., Elefanty, Andrew G., Stanley, Edouard G., Haynes, John M., Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Translational Research Articles and Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442782/
https://ncbi.nlm.nih.gov/pubmed/28297587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2016-0073
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