Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease

Human pluripotent stem cells (hPSCs) are a promising resource for the replacement of degenerated ventral midbrain dopaminergic (vmDA) neurons in Parkinson's disease. Despite recent advances in protocols for the in vitro generation of vmDA neurons, the asynchronous and heterogeneous nature of th...

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Publicado en:J Neurosci
Autores principales: de Luzy, Isabelle R., Niclis, Jonathan C., Gantner, Carlos W., Kauhausen, Jessica A., Hunt, Cameron P.J., Ermine, Charlotte, Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2019
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880462/
https://ncbi.nlm.nih.gov/pubmed/31641054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1160-19.2019
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