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Reconstitution of autophagy ameliorates vascular function and arterial stiffening in spontaneously hypertensive rats

Insufficient autophagy has been proposed as a mechanism of cellular aging, as this leads to the accumulation of dysfunctional macromolecules and organelles. Premature vascular aging occurs in hypertension. In fact, many factors that contribute to the deterioration of vascular function as we age are...

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Podrobná bibliografie
Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: McCarthy, Cameron G., Wenceslau, Camilla F., Calmasini, Fabiano B., Klee, Nicole S., Brands, Michael W., Joe, Bina, Webb, R. Clinton
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879927/
https://ncbi.nlm.nih.gov/pubmed/31469290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2019
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