Reconstitution of autophagy ameliorates vascular function and arterial stiffening in spontaneously hypertensive rats

Insufficient autophagy has been proposed as a mechanism of cellular aging, as this leads to the accumulation of dysfunctional macromolecules and organelles. Premature vascular aging occurs in hypertension. In fact, many factors that contribute to the deterioration of vascular function as we age are...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: McCarthy, Cameron G., Wenceslau, Camilla F., Calmasini, Fabiano B., Klee, Nicole S., Brands, Michael W., Joe, Bina, Webb, R. Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879927/
https://ncbi.nlm.nih.gov/pubmed/31469290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2019
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