Reconstitution of autophagy ameliorates vascular function and arterial stiffening in spontaneously hypertensive rats

Insufficient autophagy has been proposed as a mechanism of cellular aging, as this leads to the accumulation of dysfunctional macromolecules and organelles. Premature vascular aging occurs in hypertension. In fact, many factors that contribute to the deterioration of vascular function as we age are...

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Publicado en:Am J Physiol Heart Circ Physiol
Autores principales: McCarthy, Cameron G., Wenceslau, Camilla F., Calmasini, Fabiano B., Klee, Nicole S., Brands, Michael W., Joe, Bina, Webb, R. Clinton
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879927/
https://ncbi.nlm.nih.gov/pubmed/31469290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2019
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