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Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy

Skeletal muscle atrophy is a clinically important outcome of disuse because of injury, immobilization, or bed rest. Disuse atrophy is accompanied by mitochondrial dysfunction, which likely contributes to activation of the muscle atrophy program. However, the linkage of muscle mass and mitochondrial...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Trevino, Michelle B., Zhang, Xiaolei, Standley, Robert A., Wang, Miao, Han, Xianlin, Reis, Felipe C. G., Periasamy, Muthu, Yu, Gongxin, Kelly, Daniel P., Goodpaster, Bret H., Vega, Rick B., Coen, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879870/
https://ncbi.nlm.nih.gov/pubmed/31479303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00161.2019
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