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Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy

Skeletal muscle atrophy is a clinically important outcome of disuse because of injury, immobilization, or bed rest. Disuse atrophy is accompanied by mitochondrial dysfunction, which likely contributes to activation of the muscle atrophy program. However, the linkage of muscle mass and mitochondrial...

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Publicat a:Am J Physiol Endocrinol Metab
Autors principals: Trevino, Michelle B., Zhang, Xiaolei, Standley, Robert A., Wang, Miao, Han, Xianlin, Reis, Felipe C. G., Periasamy, Muthu, Yu, Gongxin, Kelly, Daniel P., Goodpaster, Bret H., Vega, Rick B., Coen, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879870/
https://ncbi.nlm.nih.gov/pubmed/31479303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00161.2019
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