Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies

Glioblastoma persists as a uniformly deadly diagnosis for patients and effective therapeutic options are gravely needed. Recently, targeted gene therapy approaches are reemerging as attractive experimental clinical agents. Our ligand-directed hybrid virus of adeno-associated virus and phage (AAVP) i...

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Dettagli Bibliografici
Pubblicato in:Cancer Gene Ther
Autori principali: Staquicini, Fernanda I., Smith, Tracey L., Tang, Fenny H. F., Gelovani, Juri G., Giordano, Ricardo J., Libutti, Steven K., Sidman, Richard L., Cavenee, Webster K., Arap, Wadih, Pasqualini, Renata
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group US 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879804/
https://ncbi.nlm.nih.gov/pubmed/31130731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-019-0101-2
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