The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection

ISG15 is an interferon-stimulated, ubiquitin-like protein, with anti-viral and anti-bacterial activity. Here, we map the endogenous in vivo ISGylome in the liver following Listeria monocytogenes infection by combining murine models of reduced or enhanced ISGylation with quantitative proteomics. Our...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Yifeng, Thery, Fabien, Wu, Nicholas C., Luhmann, Emma K., Dussurget, Olivier, Foecke, Mariko, Bredow, Clara, Jiménez-Fernández, Daniel, Leandro, Kevin, Beling, Antje, Knobeloch, Klaus-Peter, Impens, Francis, Cossart, Pascale, Radoshevich, Lilliana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879477/
https://ncbi.nlm.nih.gov/pubmed/31772204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13393-x
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