Telomere repeat–binding factor 2 binds extensively to extra-telomeric G-quadruplexes and regulates the epigenetic status of several gene promoters

The role of the telomere repeat-binding factor 2 (TRF2) in telomere maintenance is well-established. However, recent findings suggest that TRF2 also functions outside telomeres, but relatively little is known about this function. Herein, using genome-wide ChIP-Seq assays of TRF2-bound chromatin from...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Mukherjee, Ananda Kishore, Sharma, Shalu, Bagri, Sulochana, Kutum, Rintu, Kumar, Pankaj, Hussain, Asgar, Singh, Prateek, Saha, Dhurjhoti, Kar, Anirban, Dash, Debasis, Chowdhury, Shantanu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Editors' Picks
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879327/
https://ncbi.nlm.nih.gov/pubmed/31575660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008687
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