Pharmacokinetics and Dialytic Clearance of Isavuconazole during In Vitro and In Vivo Continuous Renal Replacement Therapy

The pharmacokinetics (PK) and dialytic clearance of isavuconazole in vitro and in 7 solid-organ transplant patients undergoing continuous renal replacement therapy (CRRT) were evaluated. In vivo, the mean (± standard deviation [SD]) plasma PK parameters of isavuconazole were as follows: maximum conc...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Biagi, M., Butler, D., Tan, X., Qasmieh, S., Tejani, K., Patel, S., Rivosecchi, R. M., Nguyen, M. H., Clancy, C. J., Shields, R. K., Wenzler, E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879253/
https://ncbi.nlm.nih.gov/pubmed/31527035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01085-19
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