Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model

BACKGROUND: Liver ischemia reperfusion injury (IRI) remains a challenge in liver transplantation. A number of compounds have previously demonstrated efficacy in mitigating IRI. Herein, we applied three specific additive strategies to a mouse IRI screening model to determine their relative potencies...

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Publicado en:PLoS One
Main Authors: Bral, Mariusz, Pawlick, Rena, Marfil-Garza, Braulio, Dadheech, Nidheesh, Hefler, Joshua, Thiesen, Aducio, Shapiro, A. M. James
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879152/
https://ncbi.nlm.nih.gov/pubmed/31770375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224567
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