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Gemfibrozil mitigates caspase-11-driven myocardial pyroptosis in ischemia/reperfusion injury in mice

The size of the infarct area following acute myocardial infarction (AMI) is a critical prognostic factor. Caspase-11-dependent pyroptosis has been implicated as a key mechanism driving cardiomyocyte death after AMI. However, no therapeutic agents have been developed to inhibit myocardial cell death...

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Bibliografische gegevens
Hoofdauteurs: Tetsuro Marunouchi, Mayu Kyono, Naoko Kikuchi, Kouichi Tanonaka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2025-06-01
Reeks:Journal of Molecular and Cellular Cardiology Plus
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Online toegang:http://www.sciencedirect.com/science/article/pii/S277297612500011X
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