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BRCA1 mutation influences progesterone response in human benign mammary organoids
BACKGROUND: Women, who carry a germline BRCA1 gene mutation, have a markedly increased risk of developing breast cancer during their lifetime. While BRCA1 carriers frequently develop triple-negative, basal-like, aggressive breast tumors, hormone signaling is important in the genesis of BRCA1 mutant...
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| Publicado no: | Breast Cancer Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6878650/ https://ncbi.nlm.nih.gov/pubmed/31771627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1214-0 |
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