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Endothelial cell dysfunction during Anoxia-Reoxygenation is associated with a decrease in ATP levels, rearrangement in lipid bilayer phosphatidylserine asymmetry, and an increase in endothelial cell permeability

BACKGROUND: Phosphatidylserine (PS) is normally confined in an energy-dependent manner to the inner leaflet of the lipid cell membrane. During cellular stress PS is exteriorized to the outer layer, initiating a cascade of events. Because cellular stress is often accompanied by decreased energy level...

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Pubblicato in:J Trauma Acute Care Surg
Autori principali: Sadjadi, Javid, Strumwasser, Aaron M, Victorino, Gregory P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878159/
https://ncbi.nlm.nih.gov/pubmed/31464867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002489
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