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ATTENUATION OF ENDOTHELIAL PHOSPHATIDYLSERINE EXPOSURE DECREASES ISCHEMIA-REPERFUSION INDUCED CHANGES IN MICROVASCULAR PERMEABILITY

INTRODUCTION: Translocation of phosphatidylserine from the inner leaflet to the outer leaflet of the endothelial membrane via phospholipid scramblase-1 (PLSCR1) is an apoptotic signal responsible for the loss of endothelial barrier integrity after ischemia-reperfusion injury. We hypothesized that in...

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Pubblicato in:J Trauma Acute Care Surg
Autori principali: Strumwasser, Aaron, Bhargava, Aditi, Victorino, Gregory P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970025/
https://ncbi.nlm.nih.gov/pubmed/29538229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001891
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