(11)C-Labeled Pictilisib (GDC-0941) as a Molecular Tracer Targeting Phosphatidylinositol 3-Kinase (PI3K) for Breast Cancer Imaging

Pictilisib (GDC-0941) is an inhibitor of phosphatidylinositol 3-kinase (PI3K), part of a signaling cascade involved in breast cancer development. The purpose of this study was to evaluate the pharmacokinetics of pictilisib noninvasively by radiolabeling it with (11)C and to assess the usability of t...

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Detalhes bibliográficos
Publicado no:Contrast Media Mol Imaging
Main Authors: Han, Na, Jiang, Yaqun, Gai, Yongkang, Liu, Qingyao, Yuan, Lujie, Wang, Yichun, Li, Mengting, Zhang, Yongxue, Lan, Xiaoli
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877939/
https://ncbi.nlm.nih.gov/pubmed/31787861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1760184
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