(11)C-Labeled Pictilisib (GDC-0941) as a Molecular Tracer Targeting Phosphatidylinositol 3-Kinase (PI3K) for Breast Cancer Imaging

Pictilisib (GDC-0941) is an inhibitor of phosphatidylinositol 3-kinase (PI3K), part of a signaling cascade involved in breast cancer development. The purpose of this study was to evaluate the pharmacokinetics of pictilisib noninvasively by radiolabeling it with (11)C and to assess the usability of t...

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Vydáno v:Contrast Media Mol Imaging
Hlavní autoři: Han, Na, Jiang, Yaqun, Gai, Yongkang, Liu, Qingyao, Yuan, Lujie, Wang, Yichun, Li, Mengting, Zhang, Yongxue, Lan, Xiaoli
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877939/
https://ncbi.nlm.nih.gov/pubmed/31787861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1760184
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