Oxidative DNA Damage Signalling in Neural Stem Cells in Alzheimer's Disease

The main pathological symptoms of Alzheimer's disease (AD) are β-amyloid (Aβ) lesions and intracellular neurofibrillary tangles of hyperphosphorylated tau protein. Unfortunately, existing symptomatic therapies targeting Aβ and tau remain ineffective. In addition to these pathogenic factors, oxi...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Kieroń, Marcelina, Żekanowski, Cezary, Falk, Anna, Wężyk, Michalina
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877938/
https://ncbi.nlm.nih.gov/pubmed/31814869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2149812
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