Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer's Disease

Epigenetic mechanisms play an important role in the development and progression of various neurodegenerative diseases. Abnormal methylation of numerous genes responsible for regulation of transcription, DNA replication, and apoptosis has been linked to Alzheimer's disease (AD) pathology. We hav...

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Publicat a:Oxid Med Cell Longev
Autors principals: Wezyk, Michalina, Spólnicka, Magdalena, Pośpiech, Ewelina, Pepłońska, Beata, Zbieć-Piekarska, Renata, Ilkowski, Jan, Styczyńska, Maria, Barczak, Anna, Zboch, Marzena, Filipek-Gliszczynska, Anna, Skrzypczak, Magdalena, Ginalski, Krzysztof, Kabza, Michał, Makałowska, Izabela, Barcikowska-Kotowicz, Maria, Branicki, Wojciech, Żekanowski, Cezary
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904768/
https://ncbi.nlm.nih.gov/pubmed/29849909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6918797
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