Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer's Disease

Epigenetic mechanisms play an important role in the development and progression of various neurodegenerative diseases. Abnormal methylation of numerous genes responsible for regulation of transcription, DNA replication, and apoptosis has been linked to Alzheimer's disease (AD) pathology. We hav...

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Publicado en:Oxid Med Cell Longev
Autores principales: Wezyk, Michalina, Spólnicka, Magdalena, Pośpiech, Ewelina, Pepłońska, Beata, Zbieć-Piekarska, Renata, Ilkowski, Jan, Styczyńska, Maria, Barczak, Anna, Zboch, Marzena, Filipek-Gliszczynska, Anna, Skrzypczak, Magdalena, Ginalski, Krzysztof, Kabza, Michał, Makałowska, Izabela, Barcikowska-Kotowicz, Maria, Branicki, Wojciech, Żekanowski, Cezary
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904768/
https://ncbi.nlm.nih.gov/pubmed/29849909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6918797
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