Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer's Disease

Epigenetic mechanisms play an important role in the development and progression of various neurodegenerative diseases. Abnormal methylation of numerous genes responsible for regulation of transcription, DNA replication, and apoptosis has been linked to Alzheimer's disease (AD) pathology. We hav...

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Bibliografske podrobnosti
izdano v:Oxid Med Cell Longev
Main Authors: Wezyk, Michalina, Spólnicka, Magdalena, Pośpiech, Ewelina, Pepłońska, Beata, Zbieć-Piekarska, Renata, Ilkowski, Jan, Styczyńska, Maria, Barczak, Anna, Zboch, Marzena, Filipek-Gliszczynska, Anna, Skrzypczak, Magdalena, Ginalski, Krzysztof, Kabza, Michał, Makałowska, Izabela, Barcikowska-Kotowicz, Maria, Branicki, Wojciech, Żekanowski, Cezary
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904768/
https://ncbi.nlm.nih.gov/pubmed/29849909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6918797
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