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Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice
AKR1A, an aldo-keto reductase, is involved in the synthesis of ascorbic acid as well as the reduction of a variety of aldehyde compounds. AKR1A(−/−) mice produce considerably less ascorbic acid (about 10%) compared to AKR1A(+/+) mice and require ascorbic acid supplementation in order to breed. To el...
Gardado en:
| Publicado en: | J Clin Biochem Nutr |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
the Society for Free Radical Research Japan
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6877411/ https://ncbi.nlm.nih.gov/pubmed/31777422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.19-41 |
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