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Hyperuricemia and gout caused by missense mutation in d-lactate dehydrogenase
Gout is caused by deposition of monosodium urate crystals in joints when plasma uric acid levels are chronically elevated beyond the saturation threshold, mostly due to renal underexcretion of uric acid. Although molecular pathways of this underexcretion have been elucidated, its etiology remains mo...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6877321/ https://ncbi.nlm.nih.gov/pubmed/31638601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129057 |
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