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A Simple Assay to Evaluate the Function of Human Connexin Hemichannels Expressed in Escherichia Coli that Can be Used for Drug Discovery and Mutants’ Analysis: Functional Assay of Human Connexin Hemichannels
Abnormally increased activity of connexin hemichannels contributes to cell damage in many disorders, including deafness, stroke and cardiac infarct, and therefore, hemichannels constitute a potentially important therapeutic target. Unfortunately, the available hemichannel inhibitors are not specific...
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| Gepubliceerd in: | Curr Protoc Pharmacol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6876698/ https://ncbi.nlm.nih.gov/pubmed/31756040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpph.68 |
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